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    In the state of Bahia, in the northeast of Brazil, Sonia Coutinho has developed a center for arts and alternative education for adolescents with moderate learning disabilities that is remarkably effective in aiding their transition from school to productive employment and facilitating their continued intellectual growth. It is also playing an important role in heightening public awareness of the potential of such individuals for productive roles in society.

    Rosangela Bieler, a 32-year-old journalist and paraplegic, is the founder and president of the Independent Living Center of Rio de Janeiro, an organization which is spearheading the movement of disabled Brazilians to win full citizenship.

    Merula Steagall has thalassemia—a rare hereditary blood disease—but has always led a normal life. Aware of the low quality of life for the majority of thalassemia patients in Brazil, she has used her knowledge of business to communicate with diverse partners about the democratization of access to health information and quality treatments. Through her work, Merula has doubled the life expectancy of patients, and is beginning to work on a broader range of blood diseases.

    By teaching practical culinary and social skills, Simone Berti is preparing individuals with Down syndrome and other intellectual disabilities to assimilate into society and be self-sufficient.

    In a pilot center in a small town in northeastern Brazil, Renata Arantes Villela is creating a caring and nurturing environment for the disabled. With strong links to the broader community in which it is based, the pilot center will serve as a model for the development of much-needed services for the disabled and as a vehicle for combating misconceptions about disabled individuals and what they can offer to their communities.

    Having secured the legal foundation for the human rights of the LGBT community through judicialization, Marinalva is now reinforcing mainstream support of the LGBT community in public life and at home.

    Inna serves the hidden population of Indonesian women who are pregnant but can not easily obtain information or see a doctor because of social and legal barriers.

    Cycling Without Age takes elderly nursing home residents, who tend to be socially excluded, back into the streets and allows them to be part of ongoing urban life. As the elderly passengers and younger cyclists co-create new experiences on trishaws, Cycling Without Age showcases the joy of intergenerational exchange to society.

    Candice Lys is cultivating a new generation of young leaders through a novel form of public health education that encourages expression through the arts. In doing so, Candice supports historically marginalized and isolated communities to address deep seeded challenges through evidence-based holistic practices and reciprocal and experiential ways of learning across generations.

    Dorica is revolutionising the field of care for rare disease patients, transitioning from a rigid system to a collaborative approach. She uses a flat leadership model and creates new roles to navigate it. She is building a world in which all rare diseases patients have equal and free access to diagnostic and are provided a tailored set of integrated services and therapies to increase their quality of life.